Randomized Trialhigh evidence
Cartilage Regeneration Potential in Early Osteoarthritis of the Knee: A Prospective, Randomized, Open, and Blinded Endpoint Study Comparing Adipose-Derived Mesenchymal Stem Cell (ADSC) Therapy Versus Hyaluronic Acid.
International journal of molecular sciences·August 31, 2025·PMID 40943401
Why it mattersThis study provides early evidence that ADSC therapy may offer disease-modifying effects in knee OA, not just symptom relief, which could shift treatment goals toward cartilage restoration.

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