Randomized Trialhigh evidence

Cartilage Regeneration Potential in Early Osteoarthritis of the Knee: A Prospective, Randomized, Open, and Blinded Endpoint Study Comparing Adipose-Derived Mesenchymal Stem Cell (ADSC) Therapy Versus Hyaluronic Acid.

International journal of molecular sciences·August 31, 2025·PMID 40943401

Why it matters

This study provides early evidence that ADSC therapy may offer disease-modifying effects in knee OA, not just symptom relief, which could shift treatment goals toward cartilage restoration.

Infographic summary of Cartilage Regeneration Potential in Early Osteoarthritis of the Knee: A Prospective, Randomized, Open, and Blinded Endpoint Study Comparing Adipose-Derived Mesenchymal Stem Cell (ADSC) Therapy Versus Hyaluronic Acid.
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