Randomized Trialmoderate evidence

Patient-reported symptom monitoring in patients with lung cancer (SYMPRO-Lung trial): long-term, post-hoc survival results of a multicentre, stepped-wedged, cluster-randomised clinical trial.

The Lancet. Oncology·September 11, 2026·PMID 42727592

Why it matters

Lung cancer survival remains poor, and PRO monitoring may offer a scalable way to detect symptoms early and improve outcomes. This real-world, multicentre trial extends prior evidence from advanced cancer to all stages, suggesting that integrating weekly electronic symptom assessments into routine oncology care could meaningfully prolong survival.

Infographic summary of Patient-reported symptom monitoring in patients with lung cancer (SYMPRO-Lung trial): long-term, post-hoc survival results of a multicentre, stepped-wedged, cluster-randomised clinical trial.
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