Cohort Studyhigh evidence
Genetic evidence for causality of late chronotype on metabolic syndrome in East Asians and Europeans.
Sleep medicine·June 1, 2026·PMID 41707574
Why it mattersCircadian misalignment from late chronotype may be a modifiable contributor to cardiometabolic risk across ancestries, supporting sleep timing as a target for metabolic health interventions in internal medicine and longevity practice.
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