Meta-Analysishigh evidence
Geographic heterogeneity in outcomes of intravascular ultrasound-guided vs angiography-guided percutaneous coronary intervention: a meta-analysis of randomized trials.
European heart journal·September 3, 2026·PMID 42690150
Why it mattersThe apparent benefit of IVUS-guided PCI may not be uniform across populations, with recent European trials showing neutral results. Understanding geographic effect modification is critical for interpreting trial data and applying IVUS guidance in diverse clinical settings.
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