Systematic Reviewhigh evidence

Benefits and Harms of Pharmacologic Treatments in Adults With Overweight or Obesity: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.

Annals of internal medicine·June 16, 2026·PMID 42296503

Why it matters

This comprehensive synthesis provides comparative effectiveness data on a rapidly expanding class of weight-management drugs, helping clinicians choose among agents based on weight loss efficacy, cardiovascular benefits, and tolerability.

Infographic summary of Benefits and Harms of Pharmacologic Treatments in Adults With Overweight or Obesity: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.
Visual abstract · MedLit

The papers that matter, first.

MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.

§

MedLit · Evidence, Distilled