Randomized Trialhigh evidence
Anti-inflammatory effects of nicotinamide mononucleotide (NMN) in human skeletal muscle after BFR-exercise.
Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 41705654
Why it mattersNMN is widely promoted for anti-aging and recovery, but this study suggests its anti-inflammatory effects may blunt beneficial adaptations like mitochondrial replenishment after muscle-damaging exercise. Clinicians advising athletes or patients on NMN for recovery should consider potential trade-offs between reduced inflammation and impaired muscle repair.
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