Randomized Trialhigh evidence
Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity - A Phase 2 Trial.
The New England journal of medicine·September 4, 2025·PMID 40549887
Why it mattersThis study suggests a once-monthly incretin-based option may achieve clinically meaningful weight loss and glycemic improvement, which could be relevant for patients who prefer less frequent injections or have adherence challenges with weekly agents.

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