Randomized Trialhigh evidence

Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity - A Phase 2 Trial.

The New England journal of medicine·September 4, 2025·PMID 40549887

Why it matters

This study suggests a once-monthly incretin-based option may achieve clinically meaningful weight loss and glycemic improvement, which could be relevant for patients who prefer less frequent injections or have adherence challenges with weekly agents.

Infographic summary of Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity - A Phase 2 Trial.
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