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Genetic and epigenetic underpinnings of biological aging: a multi-omics study integrating Mendelian randomization, spatial transcriptomics, and drug target discovery.

Clinical epigenetics·June 24, 2026·PMID 42343471

Why it matters

For clinicians focused on longevity and biological aging, this study provides genetically anchored targets and clarifies which inflammatory pathways may causally accelerate epigenetic aging, offering a foundation for future precision interventions.

Infographic summary of Genetic and epigenetic underpinnings of biological aging: a multi-omics study integrating Mendelian randomization, spatial transcriptomics, and drug target discovery.
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