Randomized Trialhigh evidence
Intravenous iron to treat anaemia before cardiac surgery (ITACS): international, double blind, placebo controlled randomised trial.
BMJ (Clinical research ed.)·August 19, 2026·PMID 42618081
Why it mattersPreoperative anaemia is common in cardiac surgery and increases transfusion needs and morbidity. This trial provides high-quality evidence that a single dose of intravenous iron can modestly reduce transfusions and improve postoperative recovery, supporting its use in patient blood management protocols.

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