Randomized Trialhigh evidence
Resistance training and depressive symptoms in subcortical vascular cognitive impairment: secondary results of a randomised clinical trial.
British journal of sports medicine·September 3, 2026·PMID 42692806
Why it mattersDepressive symptoms are common in cerebral small vessel disease and mild cognitive impairment, yet effective non-pharmacologic options are limited. This trial provides evidence that a structured resistance training program can reduce depressive symptoms in this population, offering a practical intervention for clinicians managing vascular cognitive impairment.
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