Randomized Trialhigh evidence

Povorcitinib for nonsegmental vitiligo: two randomized, controlled, phase 3 STOP-V trials.

Nature medicine·November 2, 2026·PMID 42972109

Why it matters

Nonsegmental vitiligo has limited systemic treatment options, and many patients seek repigmentation. These trials provide high-level evidence that an oral JAK1 inhibitor can produce clinically meaningful facial repigmentation, offering a potential new therapeutic class for patients who are candidates for systemic therapy.

Infographic summary of Povorcitinib for nonsegmental vitiligo: two randomized, controlled, phase 3 STOP-V trials.
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