Randomized Trialhigh evidence
Spinal Manipulation and Clinician-Supported Self-Management for Preventing Chronic Low Back Pain Impact: The PACBACK Randomized Clinical Trial.
JAMA internal medicine·June 1, 2026·PMID 42223934
Why it mattersIt identifies a pragmatic, non-pharmacologic strategy—clinician-supported self-management—that can be delivered by PTs/chiropractors to reduce long-term impact in high-risk acute/subacute LBP patients, potentially averting chronicity.

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