Randomized Trialhigh evidence

Oxygen saturation thresholds in children with acute respiratory distress (OxyKids): a multicentre, open, parallel-group, randomised clinical trial.

The Lancet. Respiratory medicine·May 12, 2026·PMID 42119581

Why it matters

Current SpO2 thresholds lack evidence and may prolong hospitalization. This trial provides high-quality evidence that a lower threshold safely reduces treatment burden and length of stay in common pediatric respiratory conditions.

Infographic summary of Oxygen saturation thresholds in children with acute respiratory distress (OxyKids): a multicentre, open, parallel-group, randomised clinical trial.
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