Randomized Trialhigh evidence
Effect of daily sunscreen application on vitamin D: findings from the open-label randomized controlled Sun-D Trial.
The British journal of dermatology·November 18, 2025·PMID 40927943
Why it mattersClinicians managing patients who rigorously use sunscreen for skin cancer prevention or photoaging may need to monitor vitamin D status, as this trial shows a clinically meaningful increase in deficiency risk with daily SPF 50+ application.
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