Randomized Trialmoderate evidence
Acoustic enhancement of slow wave sleep improves memory retention by coordinating brain oscillatory rhythms and autonomic activity.
Sleep·September 11, 2026·PMID 42725793
Why it mattersSleep-dependent memory consolidation is a key target for cognitive enhancement, but current non-invasive interventions yield variable results. This study identifies a specific oscillatory balance—SO/δ-spindle nesting ratio—and autonomic state that predict memory benefit, offering a mechanistic biomarker for optimizing acoustic stimulation protocols in healthy adults and potentially in clinical populations with sleep or memory deficits.
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