Randomized Trialhigh evidence
Personalized automatic management of tracheal cuff pressure and subglottic secretions drainage to prevent pneumonia in critically ill intubated patients. The MICROINHALO multicenter randomized controlled trial.
Intensive care medicine·June 1, 2026·PMID 42228008
Why it mattersVentilator-associated pneumonia remains a major cause of morbidity in the ICU. This trial suggests that automated cuff pressure and secretion management may reduce VAP rates even without reducing early tracheal colonization, offering a potential strategy to improve outcomes in mechanically ventilated patients.
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