Randomized Trialhigh evidence
Effect of Pre-operative Intravenous Crystalloid Bolus on Post-Induction Blood Pressure - a randomized blinded intervention trial.
Anesthesiology·August 7, 2026·PMID 42565471
Why it mattersPost-induction hypotension is a common, modifiable risk factor for adverse outcomes, and the value of pre-operative fluid loading remains debated. This trial provides robust evidence that a crystalloid bolus shortly before induction does not mitigate hypotension, informing fluid management strategies in high-risk surgical patients.
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