Randomized Trialhigh evidence
Catheter-Based Sacral Nerve Block Versus Pudendal Nerve Block in the Treatment of Pudendal Neuralgia: A Randomized Double-Blinded Controlled Trial.
European journal of pain (London, England)·August 1, 2026·PMID 42559665
Why it mattersPudendal neuralgia is disabling, and optimal interventional management remains unclear. This first head-to-head RCT suggests that targeting the S2-4 nerve roots via sacral block may offer superior and more durable relief than direct pudendal nerve block, potentially by addressing central sensitization.
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