Randomized Trialhigh evidence

Transcranial focused ultrasound stimulation enhances semantic memory by modulating brain morphology, neurochemistry and neural dynamics.

Nature communications·February 16, 2026·PMID 41698912

Why it matters

It provides the first evidence that non-invasive ultrasound can modulate deep temporal lobe structures to enhance semantic memory, with convergent neurochemical, functional, and structural changes. This opens avenues for neuromodulation in memory disorders and cognitive optimization.

Infographic summary of Transcranial focused ultrasound stimulation enhances semantic memory by modulating brain morphology, neurochemistry and neural dynamics.
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