Studymoderate evidence
Development of a nalmefene formulation suitable for a community-use auto-injector.
British journal of clinical pharmacology·July 14, 2026·PMID 42448614
Why it mattersRapid reversal of opioid-induced respiratory depression is critical in community overdose settings where advanced life support is not immediately available. A faster-acting intramuscular nalmefene formulation could improve outcomes by reducing time to restoration of breathing.

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