Randomized Trialhigh evidence
Efficacy of Stellate Ganglion Block for Preventing Postoperative Atrial Fibrillation After Cardiac Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.
Journal of the American Heart Association·October 30, 2026·PMID 42960736
Why it mattersPostoperative atrial fibrillation and organ injury remain common after cardiac surgery. While SGB did not prevent POAF, its association with fewer malignant arrhythmias, less myocardial injury, and lower AKI risk suggests autonomic modulation may improve perioperative outcomes beyond rhythm control.

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