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Effects of Calorie Restriction With and Without Strength, Endurance or Mixed Training on Fat-Free and Skeletal Muscle Mass in Overweight or Obese Individuals-A Systematic Review With Pairwise Meta-Analysis and Network Meta-Analysis of Randomized Controlled Studies.

Diabetes, obesity & metabolism·August 1, 2026·PMID 42144246

Why it matters

Preserving muscle during weight loss is critical for metabolic health and preventing frailty. This analysis quantifies how much exercise—especially mixed or strength training—can mitigate FFM loss, guiding exercise prescription in obesity management.

Infographic summary of Effects of Calorie Restriction With and Without Strength, Endurance or Mixed Training on Fat-Free and Skeletal Muscle Mass in Overweight or Obese Individuals-A Systematic Review With Pairwise Meta-Analysis and Network Meta-Analysis of Randomized Controlled Studies.
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MedLit · Evidence, Distilled