Randomized Trialhigh evidence
Prebiotics improve frailty status in community-dwelling older individuals in a double-blind, randomized, controlled trial.
The Journal of clinical investigation·August 6, 2024·PMID 39286985
Why it mattersFrailty is a major driver of morbidity and mortality in older adults, yet interventions remain limited. This trial provides evidence that a simple, scalable prebiotic supplement can modify the gut microbiome and improve clinically meaningful frailty metrics.

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