Cohort Studymoderate evidence

Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions and circulating signatures.

Nature aging·August 25, 2026·PMID 42642518

Why it matters

Sex-specific aging trajectories and modifiable metabolic drivers offer a basis for personalized geroprotective strategies, particularly for midlife risk stratification and intervention timing.

Infographic summary of Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions and circulating signatures.
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