Cohort Studymoderate evidence
Acute Imbalance Syndrome vs Acute Vestibular Syndrome: Clinical and Topographical Differentiation.
Neurology·November 10, 2026·PMID 42848973
Why it mattersCurrent bedside algorithms for stroke in vertigo rely on spontaneous nystagmus, potentially missing over half of posterior circulation strokes that present with isolated imbalance. Recognizing AIS as a distinct phenotype may improve early stroke detection in emergency settings.

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