Randomized Trialhigh evidence

Targeted high-definition transcranial direct current stimulation over the left dorsolateral prefrontal cortex to modify cognitive biases in young adults with social anxiety: a randomized controlled trial.

Molecular psychiatry·July 1, 2026·PMID 41764338

Why it matters

This study provides early evidence that a non-invasive brain stimulation protocol can selectively modulate cognitive biases implicated in social anxiety, offering a potential mechanistic target for future interventions. It highlights a dissociation between objective behavioral changes and subjective symptom reports, which is clinically relevant for treatment development.

Infographic summary of Targeted high-definition transcranial direct current stimulation over the left dorsolateral prefrontal cortex to modify cognitive biases in young adults with social anxiety: a randomized controlled trial.
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