Randomized Trialhigh evidence
Vasopressin-Based Versus Norepinephrine-Based Strategy in Vasoplegic Syndrome After Cardiac Surgery: A Randomized Controlled Trial.
Journal of intensive care medicine·July 29, 2026·PMID 42524721
Why it mattersVasoplegic syndrome after cardiopulmonary bypass is common and challenging to manage. A vasopressin-first approach may offer hemodynamic advantages and reduce length of stay compared to norepinephrine, providing an evidence-based alternative for early vasopressor selection in postoperative cardiac surgical patients.

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