Randomized Trialhigh evidence
Liberal or Restrictive Transfusion Strategy in Aneurysmal Subarachnoid Hemorrhage.
The New England journal of medicine·March 13, 2025·PMID 39655786
Why it mattersAnemia is common after aneurysmal subarachnoid hemorrhage and may exacerbate brain injury, but optimal transfusion thresholds remain uncertain. This large, multicenter trial provides high-quality evidence that a liberal strategy does not improve neurologic outcomes, supporting current restrictive practices and reducing unnecessary transfusions.
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