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GLP-1 Receptor Agonists and All-Cause Overdose Risk in Veterans With Type 2 Diabetes and Opioid Use Disorder.

The Journal of clinical psychiatry·July 15, 2026·PMID 42474323

Why it matters

Opioid use disorder remains a leading cause of overdose death, and effective pharmacotherapies are limited. These findings add to emerging evidence that GLP-1 receptor agonists may reduce overdose risk in patients with OUD, potentially offering a dual-benefit option for those with comorbid type 2 diabetes.

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