Cohort Studyhigh evidence
Development and independent validation of a hypoxemia risk prediction model (HAPPY-12K) for sedated gastrointestinal endoscopy: a multicentre prospective cohort study.
EClinicalMedicine·August 1, 2026·PMID 42542617
Why it mattersHypoxemia is a frequent and serious complication of procedural sedation, yet no dedicated pre-procedural risk tool exists for gastrointestinal endoscopy. HAPPY-12K provides a validated, easy-to-use model that can identify high-risk patients before sedation, potentially reducing adverse events and unnecessary interventions.
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