Systematic Reviewhigh evidence
Cerebrovascular reactivity in obstructive sleep apnea: A systematic review using BOLD MRI.
Sleep medicine·June 1, 2026·PMID 41762857
Why it mattersOSA is a major risk factor for stroke and cognitive decline, but its effects on cerebrovascular regulation are poorly understood. This review clarifies that BOLD CVR is not simply blunted but dysregulated, offering a potential imaging biomarker for risk stratification and monitoring therapeutic response in patients with OSA.
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