Randomized Trialhigh evidence
Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students.
Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 42120324
Why it mattersFor overweight/obese sedentary females, optimizing fat oxidation during exercise could support weight management. This study identifies a caffeine dose that enhances fat burning without added cardiovascular strain, informing safe and effective pre-exercise caffeine use in this population.

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