Meta-Analysishigh evidence
Nebulized Heparin in Adults With Acute Respiratory Failure: A Meta-Analysis of Randomized Trials.
Critical care medicine·July 1, 2026·PMID 42148826
Why it mattersAcute respiratory failure carries high mortality, and current therapies are limited. Nebulized heparin is inexpensive, widely available, and targets pulmonary coagulopathy—a key pathophysiologic mechanism. This meta-analysis provides the most comprehensive evidence to date suggesting a survival benefit with a favorable safety profile.
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