Randomized Trialhigh evidence

Effects of Exercise on Cognitive Impairment in Patients Receiving Chemotherapy: A Multicenter Phase III Randomized Controlled Trial.

Journal of the National Comprehensive Cancer Network : JNCCN·March 1, 2026·PMID 41825129

Why it matters

Cancer-related cognitive impairment affects up to 75% of patients during chemotherapy and lacks effective interventions. This trial provides evidence that a tailored home-based exercise program can mitigate both cognitive decline and mental fatigue, offering a low-risk, accessible supportive care strategy.

Infographic summary of Effects of Exercise on Cognitive Impairment in Patients Receiving Chemotherapy: A Multicenter Phase III Randomized Controlled Trial.
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