Randomized Trialhigh evidence
Urate-Related Genetic Risk Modulates the Anti-Aging Effects of Exogenous Nucleotides: Multi-Omics Evidence From Older Adults.
Aging cell·June 1, 2026·PMID 42265534
Why it mattersThis study provides early evidence that genetic variation in urate metabolism may determine whether nucleotide supplementation preferentially supports epigenetic maintenance or immune regulation, advancing a precision-nutrition approach to biological aging.

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