Randomized Trialhigh evidence

Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery.

The New England journal of medicine·June 25, 2026·PMID 42267805

Why it matters

Anesthesiologists frequently manage bleeding risk in major noncardiac surgery. This pragmatic trial supports a hospital-wide tranexamic acid policy to reduce transfusions without increasing thromboembolic events.

Infographic summary of Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery.
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