Simultaneous derivation, validation, and comparison of predictor hazard ratios for cardiovascular risk prediction equations in patients with diabetes from high versus non-high income countries: cohort study.

BMJ (Clinical research ed.)·September 11, 2026·PMID 42727977

Why it matters

Cardiovascular risk prediction tools developed in high-income countries may misclassify risk when applied to populations in non-high-income settings, particularly among patients with diabetes. This study identifies age as a key source of miscalibration and offers a practical method to improve accuracy.