Randomized Trialhigh evidence
Effect of Early Administration of Shenfu Injection on Hemodynamics in Septic Patients: A Multicenter, Randomized, Controlled Trial.
Critical care medicine·July 15, 2026·PMID 42456111
Why it mattersSepsis remains a leading cause of ICU mortality, and adjunctive therapies that improve microcirculation and survival are needed. SFI, a traditional Chinese medicine, showed a mortality benefit without reducing vasopressor doses, suggesting mechanisms beyond hemodynamic support.
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