Systematic Reviewhigh evidence
Current evidence on radiofrequency denervation for chronic low back pain: a systematic review and meta-analysis.
BMJ open·July 16, 2026·PMID 42463214
Why it mattersRF denervation is widely used for chronic low back pain, yet its clinical benefit remains uncertain. This comprehensive review quantifies the effect sizes and highlights that improvements, while statistically significant in some comparisons, fall below thresholds considered clinically meaningful, informing shared decision-making and guideline development.

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