Randomized Trialhigh evidence

Epigenetic aging during adjuvant chemotherapy for colon cancer and modification by a resistance training intervention.

Journal of the National Cancer Institute·August 3, 2026·PMID 42544784

Why it matters

Adjuvant chemotherapy may accelerate biological aging in colon cancer patients, contributing to long-term functional decline. This study provides the first evidence that a resistance training intervention can mitigate chemotherapy-associated epigenetic aging, suggesting a potential strategy to preserve long-term health in cancer survivors.

Infographic summary of Epigenetic aging during adjuvant chemotherapy for colon cancer and modification by a resistance training intervention.
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