Cohort Studymoderate evidence
The association between age and mortality in men with adult-onset testosterone deficiency is altered by testosterone therapy.
The aging male : the official journal of the International Society for the Study of the Aging Male·December 31, 2026·PMID 42391314
Why it mattersThe differential age-mortality relationship suggests testosterone therapy may restore a normal aging trajectory by mitigating metabolic risk factors, which could inform risk stratification and treatment decisions in men with testosterone deficiency.
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