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Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer's disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study.

Lancet (London, England)·May 30, 2026·PMID 42208563

Why it matters

Tracer selection significantly affects tau detection rates, which has direct implications for patient selection in clinical trials and for interpreting tau PET results in diagnostic and therapeutic decision-making.

Infographic summary of Comparison of [18F]flortaucipir and [18F]MK6240 for the detection of tau pathology in Alzheimer's disease (HEAD): a multicentre, prospective, cross-sectional, within-participant study.
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