Meta-Analysishigh evidence
Compensatory Smoking With Very Low Nicotine Content Cigarettes: A Systematic Review and Meta-Analysis.
JAMA network open·July 1, 2026·PMID 42455573
Why it mattersA mandated reduction in cigarette nicotine content could be a major public health measure, but concerns about compensatory smoking have been a key barrier. This analysis provides reassurance that widespread compensation is unlikely, which is critical for clinicians counseling patients and for policy implementation.
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