Meta-Analysishigh evidence
Safety of creatine supplementation: analysis of the prevalence of reported side effects in clinical trials and adverse event reports.
Journal of the International Society of Sports Nutrition·September 1, 2025·PMID 40198156
Why it mattersDespite persistent online claims, this large-scale analysis provides robust evidence that creatine monohydrate supplementation is safe and well-tolerated, helping clinicians confidently address patient concerns about side effects.
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