Randomized Trialhigh evidence
Polygenic Risk Identifies Older Adults Who May Benefit From Aspirin for the Primary Prevention of Ischemic Stroke.
Stroke·May 8, 2026·PMID 42100829
Why it mattersCurrent guidelines recommend against routine aspirin for primary prevention in older adults due to bleeding concerns. This study suggests that genomic risk stratification could identify a subgroup that derives net benefit, potentially enabling targeted aspirin use in high-risk individuals.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled