Meta-Analysishigh evidence
The Resistance Training Dose Response: Meta-Regressions Exploring the Effects of Weekly Volume and Frequency on Muscle Hypertrophy and Strength Gains.
Sports medicine (Auckland, N.Z.)·February 1, 2026·PMID 41343037
Why it mattersOptimizing resistance training prescription requires understanding how volume and frequency independently drive hypertrophy versus strength. This analysis clarifies that volume is key for hypertrophy, while both volume and frequency matter for strength, but with diminishing returns—helping clinicians and coaches tailor programs more precisely.

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