Meta-Analysismoderate evidence

Prophylactic interventions to prevent rebound pain after peripheral nerve block in adults: a systematic review and network meta-analysis of randomised controlled trials.

Anaesthesia·May 26, 2026·PMID 42187168

Why it matters

Rebound pain can undermine the benefits of regional anesthesia. This analysis identifies intravenous dexamethasone as a first-line prophylactic, offering a practical, evidence-based strategy to improve postoperative pain management and patient experience.

Infographic summary of Prophylactic interventions to prevent rebound pain after peripheral nerve block in adults: a systematic review and network meta-analysis of randomised controlled trials.
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