Randomized Trialhigh evidence
Global Proteomics Reveals Distinct Muscle Adaptations to Menstrual Cycle Phase-Based Sprint Interval Training in Endurance-Trained Females.
Molecular & cellular proteomics : MCP·October 1, 2025·PMID 40818533
Why it mattersMenstrual cycle phase may influence molecular adaptations to high-intensity training in already-trained females, potentially affecting mitochondrial function and performance outcomes. This challenges the assumption that training responses are uniform across cycle phases and suggests phase-based programming could optimize adaptations.
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