Meta-Analysishigh evidence
Long-term efficacy of cognitive behavioural therapy for insomnia (CBT-I) on depressive symptoms: A systematic review and meta-analysis of randomised controlled trials.
Sleep medicine reviews·July 9, 2026·PMID 42435604
Why it mattersPersistent insomnia frequently co-occurs with depressive symptoms, and clinicians need evidence on whether treating insomnia yields durable mood improvements. This meta-analysis confirms that CBT-I provides sustained reductions in depressive symptoms for up to 12 months, supporting its role as a foundational intervention in patients with comorbid insomnia and low mood.

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