Meta-Analysishigh evidence

Mechanical Circulatory Support for Complex High-Risk Indicated Percutaneous Coronary Intervention: Network Meta-Analysis of Randomized Trials.

Journal of the American Heart Association·September 9, 2026·PMID 42714579

Why it matters

Complex high-risk PCI carries substantial risk, and MCS is increasingly used despite uncertain benefit. This analysis clarifies that prophylactic MCS does not improve hard outcomes, guiding more selective use and resource allocation in cath labs.

Infographic summary of Mechanical Circulatory Support for Complex High-Risk Indicated Percutaneous Coronary Intervention: Network Meta-Analysis of Randomized Trials.
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